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Sanofi Announces the Result of Sarclisa (isatuximab)+ KRd in P-III Trial to Treat Multiple Myeloma

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Sanofi

Sanofi Announces the Result of Sarclisa (isatuximab)+ KRd in P-III Trial to Treat Multiple Myeloma

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  • The P-III study evaluating the safety and efficacy of Sarclisa+carfilzomib, lenalidomide & dexamethasone vs KRd alone in transplant-eligible patients (n=302) with newly diagnosed multiple myeloma across 8 countries 42 sites in the EU
  • The result of the 1EP study depicted MRD negativity of 77% vs 67% & 67% vs 48% at the sensitivity of 10-5 & 10-6 with consistent results in all subgroups. The safety & tolerability of the drug were found to be consistent with previous data
  • Sarclisa, a mAb, targets the CD38 receptor on MM cells, triggering various antitumor effects. It induces programmed cell death & has immunomodulatory properties

Ref: Sanofi  | Image: Sanofi 

Related News:- Sanofi Reports Results for Sarclisa (Isatuximab) in P-III Trial for the Treatment of Newly Diagnosed Multiple Myeloma Patients

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Kritika Jha

Kritika is a content writer at PharmaShots. She is interested in covering recent innovations from the pharma & MedTech industry. She covers news related to Product approvals, clinical trial results, and updates. She can be contacted at connect@pharmashots.com.

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